(Solution) NR507 Week 6: Discussion

NR507 Week 6: Discussion

Preparing the Discussion

Follow these guidelines when completing each component of the discussion. Contact your course faculty if you have questions.

General Instructions 

The purpose of this discussion is to examine an assigned disease process and determine which disease process explored in the discussion Bayani, the client, is experiencing. Follow the instructions below and your faculty member will reveal which disease process Bayani is experiencing at the end of the discussion week.

Step 1: Review the following client scenario:

Bayani, a 62-year-old male client, presents to the NP with abdominal pain with his wife. Bayani is mildly confused, and according to his wife, he is normally fully oriented. His abdomen is soft and non-distended, and his wife states he has been urinating and drinking more water than usual. She also states he has had foul-smelling urine and is concerned he also has a urinary tract infection.

Step 2: Review your assigned disease process from the chart below. Your assigned disease process is based on the first letter of your last name.

Last Name Disease Process
A – H Condition: Peptic Ulcer Disease (PUD)
I – P Condition: Cirrhosis
Q – Z Condition: Type 2 Diabetes

Step 3: Review the client case scenario and answer the discussion prompts below with explanation and detail, providing complete references for all citations.

Step 4: Reply to a peer with a different assigned disease process.

Include the following sections:

1. Application of Course Knowledge: Answer all questions/criteria with explanations and detail.

  1. Discuss the underlying pathophysiological mechanisms of your assigned disease process. Which clinical manifestations observed in Bayani’s case could be explained by the pathophysiological mechanisms?
  2. Analyze Bayani’s clinical manifestations in the context of your assigned disease process. Do these findings support a diagnosis of your assigned disease process? Why or why not?
  3. Identify and justify the diagnostic tests (including labs, imaging, or other diagnostic tests) that would be most appropriate for investigating a diagnosis of your assigned disease process in Bayani. What could the results of these tests look like in your assigned disease process?
  4. Compare and contrast your response with a peer assigned a different condition. Does their condition fit Bayani’s case? Why or why not?

2. Integration of Evidence: Integrate relevant scholarly sources as defined by program expectations:

  1. Cite a scholarly source in the initial post.
  2. Cite a scholarly source in one faculty response post.
  3. Cite a scholarly source in one peer post.
  4. Accurately analyze, synthesize, and/or apply principles from evidence with no more than one short quote (15 words or less) for the week.
  5. Include a minimum of two different scholarly sources per week. Cite all references and provide references for all citations.

3. Engagement in Meaningful Dialogue: Engage peers and faculty by asking questions and offering new insights, applications, perspectives, information, or implications for practice.

  1. Peer Response: Respond to at least one peer on a topic other than the initially assigned topic.
  2. Faculty Response: Respond to at least one faculty post.
  3. Communicate using respectful, collegial language and terminology appropriate to advanced nursing practice.

Solution: NR507 Week 6: Discussion

Underlying Pathophysiological Mechanisms of Liver Cirrhosis

Liver cirrhosis develops as a consequence of chronic liver injury, which triggers a cascade of cellular and structural changes (Jagdish et al., 2023). Persistent damage, whether from alcohol, viral hepatitis, or metabolic disorders, activates hepatic stellate cells (HSCs) (American Liver Foundation [ALF], 2024). As described by Jagdish et al. (2023), once activated, HSCs transform into collagen-producing myofibroblasts, depositing scar tissue that disrupts the liver’s architecture. Over time, fibrosis distorts the sinusoidal network, where liver sinusoidal endothelial cells lose their specialized pores (defenestration), impairing the exchange of nutrients and waste between blood and hepatocytes (Lee, 2025). This remodeling contributes to portal hypertension as increased resistance to blood flow elevates pressure in the portal vein, exacerbating systemic complications, such as splanchnic vasodilation and fluid retention, mediated by neurohormonal systems like the renin-angiotensin-aldosterone system (RAAS) (Jagdish et al., 2023). Concurrently, the liver’s functional decline reduces its ability to detoxify……….Click the paypal icon to purchase full solution for $5

Related: (Solution) NR507 Week 7 discussion Choose Your Own Pathophysiology Adventure