(Solution) NR507 Week 4: Collaboration Café

NR507 Week 4: Collaboration Café

Preparing the Collaboration Café

Follow these guidelines when completing each component of the collaboration café. Contact your course faculty if you have questions.

General Instructions

During the past four weeks, you have examined conditions affecting the immune, hematologic, cardiovascular, pulmonary, and renal systems. Some conditions can affect all of these conditions, including autoimmune disorders like systemic lupus erythematosus (SLE) that cause inflammation in multiple body systems. Follow the steps below to analyze the effects of SLE on various body systems.

Step 1: Review your assigned body system from weeks 1-4. Your assignment is based on the first letter of your last name in the chart below.

Last Name Body System
A – F Immune System
G – K Hematologic System
L – P Cardiovascular System
Q – U Pulmonary System
V – Z Renal System

Step 2: Reflect on how SLE impacts your assigned body system.

Step 3: Answer the discussion prompts below with explanation and detail, providing complete references for all citations.

Step 4: Reply to a peer with a different assigned body system.

Include the following sections: 

1. Application of Course Knowledge: Answer all questions/criteria with explanations and detail.

  1. Describe the specific pathophysiological processes in SLE that lead to the manifestations observed in your assigned body system. How does SLE affect your assigned body system?
  2. Discuss the symptoms and clinical manifestations of SLE on your assigned body system. How do these symptoms impact the client’s function and quality of life? Can changes in your assigned body system affect or be affected by other body systems in clients with SLE?
  3. Discuss the diagnostic tests used to diagnose SLE-related complications in your body system. What challenges are associated with diagnosing SLE if only looking at your assigned body system?
  4. Explore the current treatments for managing SLE symptoms associated with your assigned body system. What are the goals of these treatments and how effective are they in mitigating the impact of SLE on the body?

Solution: NR507 Week 4: Collaboration Café

Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disorder that significantly affects the cardiovascular system through various pathophysiological mechanisms. As explained by Frostegård 2023), autoantibodies, such as anti-dsDNA and antiphospholipid antibodies, form immune complexes that deposit in cardiac tissues and blood vessels, triggering inflammation and complement activation. This process can result in vasculitis, endothelial damage, and accelerated atherosclerosis. SLE also increases the risk of nonbacterial endocarditis, particularly Libman-Sacks endocarditis, which affects the heart valves. Moreover, inflammation of the pericardium and myocardium may lead to pericarditis, myocarditis, and impaired cardiac function.

Clinically, cardiovascular involvement in SLE can present as chest pain from pericarditis, shortness of breath, fatigue, arrhythmias, and even heart failure. Patients may experience angina or myocardial infarction at a younger age due to accelerated coronary artery disease (Jha et al., 2022). Libman-Sacks endocarditis may remain asymptomatic or lead to embolic events and…..Click the payola icon to purchase full solution for $5

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