(Solution) NR507 Week 5 Discussion Choose Your Own Pathophysiology Adventure

NR507 Week 5 Discussion Choose Your Own Pathophysiology Adventure

Preparing the Assignment

Follow these guidelines when completing each component of the discussion. Contact your course faculty if you have questions.

General Instructions 

This discussion represents the second step in a three-step discussion series where you will choose your pathophysiology adventure to analyze and present to the class. Students will continue to explore the disease process that was chosen in Week 2. In this step of the discussion series, you will describe the pathophysiology of your chosen condition from Week 2 and its manifestations, diagnosis, and lifespan considerations. You will also create your case study.

Include the following sections:

1. Application of Course Knowledge: Answer all questions/criteria with explanations and detail.

  1. Describe the pathophysiology of the chosen condition. What is the condition’s etiology, signs and symptoms, complications, and risk factors?
  2. Discuss how the condition is diagnosed. What are relevant assessment findings, labs, and imaging studies?
  3. Explain how the pathophysiology of the condition might differ across the lifespan. Does the condition manifest in pediatric, pregnant, breastfeeding, and older adult populations? How might the condition look different across the lifespan?
  4. Create your case study based on the chosen condition (~ 1,000 words or less using bullet points and full sentences). Start with the diagnosis and work backward to develop a clinical scenario that leads to this diagnosis. Include the client’s name, social background, symptoms, lab results, medical or surgical history, and other relevant details.

2. Integration of Evidence: Integrate relevant scholarly sources as defined by program expectations:

  1. Cite a scholarly source in the initial post.
  2. Cite a scholarly source in one faculty response post.
  3. Cite a scholarly source in one peer post.
  4. Accurately analyze, synthesize, and/or apply principles from evidence with no more than one short quote (15 words or less) for the week.
  5. Include a minimum of two different scholarly sources per week. Cite all references and provide references for all citations.

3. Engagement in Meaningful Dialogue: Engage peers and faculty by asking questions and offering new insights, applications, perspectives, information, or implications for practice.

  1. Peer Response: Respond to at least one peer on a condition other than the one you selected.
  2. Faculty Response: Respond to at least one faculty post.
  3. Communicate using respectful, collegial language and terminology appropriate to advanced nursing practice.

Soultion: NR507 Week 5 Discussion Choose Your Own Pathophysiology Adventure

The disease chosen from week 2 Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic disorder marked by persistent hyperglycemia due to a combination of insulin resistance and progressive pancreatic beta-cell dysfunction (Lima et al., 2022). It is the most common form of diabetes and typically develops gradually over many years, with its pathophysiological processes beginning with insulin resistance in key tissues, primarily muscle, liver, and adipose tissue, meaning that these cells no longer respond adequately to normal levels of insulin (Lima et al., 2022). In the early stages, pancreatic beta-cells compensate by increasing insulin secretion but with time, this compensation fails as beta-cell function declines, resulting in relative insulin deficiency, leading to sustained high blood glucose levels (hyperglycemia) and eventually, microvascular and macrovascular damage (American Diabetes Association, 2025). Hyperglycemia in T2DM extends beyond glucose elevation, to include induction of oxidative stress, chronic inflammation, and endothelial dysfunction, which collectively impair vascular health and tissue repair (Lima et al., 2022). Lipotoxicity (accumulation of toxic lipids in non-adipose tissues) and glucotoxicity (toxic effects of excess glucose) further accelerate cellular damage (Samson et al., 2023). These changes underpin many of the long-term complications associated with the condition.

Etiology and Risk Factors

The causes of T2DM are multifactorial, including both genetic predisposition and environmental triggers. Family history plays a significant role, with first-degree relatives of people with T2DM facing a substantially increased risk. However, environmental and behavioral factors, such as a sedentary lifestyle, high-calorie diets rich in processed carbohydrates, and obesity (especially central or visceral adiposity), are major contributors (Samson et al., 2023). Ethnic background…Click the paypal icon to purchase full solution for $10

Related: (Solution) NR507 Week 6: Discussion